The 2S25 Sprut-SD is equipped with a two man turret armed with 125mm antitank gun and fitted with the equipment to control guided projectiles and the day/night sight with sighting and a ranging channel. The gun is fitted with an automatic ammunition loader, which ensures high rate of fire of 6 to 8 rounds per minute with both conventional projectiles and rounds with guided missiles. A coaxial machine of 7.62 mm calibre is mounted to the left side of the main armament. Two banks of three smoke-grenades discharger are mounted to the rear side of the turret.

The hull and turret of the 2S25 self-propelled anti-tank gun is of all-welded aluminium armour with a composite skin. Constructed with the crew compartment at the front, turret and fighting compartment in the centre and power pack at the rear. Through the frontal arc of 40° left and right the armour provides protection against attack from fire up to 75 mm and through the remainder of the vehicle against attack from 30 mm.

The 2S25 Sprut-SD antitank gun can be shipped by all types of transport, para-dropped with the crew inside the vehicle and cross water obstacles in sea state of up to-3 without preparation while firing the gun within a sector of ±35. To ensure concealment, the ground clearance can be changed within 400mm during 6-7s. Each member of crew has available the built-in the roof observant instruments with the day and night channels. The combined sight of the commander is stabilized in two planes and is combined with the laser sight for guiding 125-mm projectiles along the laser beam. The sight of spotter is stabilized in the vertical plane and includes the laser range-finder, which provides ballistic calculator with the constantly changing data about the purpose. The 2S25 Sprut-SD is fully amphibious and is moved in the water with the aid of two water jets, which make possible for it to develop speed 8-10 km/h.